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First-in-human biomarker-driven phase I trial of the potent and selective glutaminase-1 (GLS1) inhibitor IACS-6274 (IPN60090) in patients with molecularly selected advanced solid tumors
Yang XD et al
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Some patients report that these sensations improve as their body adjusts to the medication, whilst others find them persistent
ACT 1: Beyond GLP-1 Why Triple Agonists Are Rewriting the Weight Loss Ceiling To understand why newer drugs like Retatrutide are generating so much excitement in obesity medicine, you first need to understand what current medications actually do and where their limitations lie
These are typically delivered in single-dose pens or occasionally in single-dose vials
Influence insulin and glucagon: They stimulate insulin release and suppress glucagon after meals, optimising blood sugar management, especially in people with type 2 diabetes
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![PDF] Sitagliptin/Metformin (janumet) as combination therapy in the treatment of type-2 diabetes mellitus](https://figures.semanticscholar.org/f414b00424f4a58022bbede6945d895a8825115e/1-Figure1-1.png)
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